What is our mission?
There are not yet any "in vitro" tests or test strategies available to test chemical compounds on their potential to induce allergies.
The aim of the Sens-it-iv project is to develop "in vitro" alternatives to animal tests currently used for the risk assessment of potential skin or lung sensitizers.
The aim of the Sens-it-iv project is to develop "in vitro" alternatives to animal tests currently used for the risk assessment of potential skin or lung sensitizers.

Why focus on allergens?
Worldwide, the occurence of allergies is increasing and has become an important health problem.
Before an allergy occurs, a tissue or organ has to be exposed to a compound with the potential to elicit an immune reaction, namely compounds called sensitizing agents or allergens.
The skin and lung are the most important targets for allergens.
Before an allergy occurs, a tissue or organ has to be exposed to a compound with the potential to elicit an immune reaction, namely compounds called sensitizing agents or allergens.
The skin and lung are the most important targets for allergens.
Project participants
28 groups overall, of which 9 represent industry. 15 groups represent universities or research institutes, while 4 groups represent organizations.
Click here for a complete list of the participating groups.
Click here for a complete list of the participating groups.
Project Summary
This document is a summary of the Sens-it-iv project. It contains a project summary, the project objectives, a list of participants and other topics of interest.
Download the document here:
Sens-it-iv_Summary.pdf, 83 kb
Download the document here:
Sens-it-iv_Summary.pdf, 83 kb
Project activities are carried out in 10 Work Packages (WPs). For a full description, click here:
Sens-it-iv WP Activities
Sens-it-iv WP Activities
Latest News
ecopa, the European Consensus Platform on 3R-Alternatives, won the EPAA best poster price 2009 that was dedicated to the dissemination of 3R information. ecopa is a partner in the Sens-it-iv project, more precisely in the Dissemination Workpackage.
To see the poster click here.
To see the poster click here.
Our first Sens-it-iv Newsletter appeared on 14 December 2006.
Click here to view the latest
edition of our newsletter
Click here to view the latest
edition of our newsletter


